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132342-55-3

Articles about 132342-55-3Total 3 be found

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Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines
A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and tessaric acid. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, HBL-100, HeLa, SW1573, T-47D and WiDr. The most potent analog induced considerably growth inhibition in the range 1.9-4.5 μM. Cell cycle studies for tessaric acid derivatives indicated a prominent arrest of the cell cycle at the G2/M phase. Damage to the cells was permanent as determine by the so called 24+24 drug schedule.
Leon, Leticia G.,Donadel, Osvaldo J.,Tonn, Carlos E.,Padron, Jose M.
p. 6251 - 6256
(2009)
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Acid-promoted opening of 4,5- and 3,4-epoxy eudesmane scaffolds from α-isocostic acid
The acid-catalyzed rearrangement of epoxide 3a and 8a derived from sesquiterpernic isocostic acid (1), the main component of Dittrichia viscosa, was studied using Lewis and Br?nsted acids. Several new compounds were obtained with different selectivities depending on the catalyst used. These compounds were fully characterized by spectroscopic methods, and mechanistic explanations for their formation are proposed.
Zaki, Mohamed,Tebbaa, Mohammed,Hiebel, Marie-Aude,Benharref, Ahmed,Akssira, Mohamed,Berteina-Raboin, Sabine
p. 2035 - 2042
(2015/03/30)

Ilicic Acid as a Natural Quiron for the Efficient Preparation of Bioactive α- and β-Eudesmol
An efficient procedure for the isolation of the sesquiterpene ilicic acid (3) on a multigram scale of extracts obtained from aerial parts of Inula viscosa (Asteraceae) was developed. Acid 3 is an appropriate starting material for short, enantio-specific s
Barrero, Alejandro F.,Herrador, M. Mar,Arteaga, Pilar,Catalan, Julieta V.
experimental part
p. 3589 - 3594
(2009/12/01)

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Chemical Properties

Boiling Point: 331.3±11.0 °C(Predicted)
Density: 1.00±0.1 g/cm3(Predicted)
PSA: 26.30000
LogP: 4.02240

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