- PYRROLOTRIAZINES AS POTASSIUM ION CHANNEL INHIBITORS
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A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, maintaining normal sinus rhythm, IKur-associated disorders, and other disorders mediated by ion channel function.
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Page/Page column
(2014/09/29)
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- COLOUR AND CONSTITUTION OF AZO COMPOUNDS DERIVED FROM DIAMINOAZINES
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Visible absorption spectra have been recorded for azo compounds derived from 2,5-dichlorosulphanilic acid azo-coupled with N,N-diethyl-m-phenylenediamine, and with azine analogues.The effects of the ring-aza substituents as well as cyano on the spectra indicate a surprising difference in sensitivity of the two ring positions meta to the azo group.M.O. calculations show that the amino group ortho to the azo linkage introduces asymmetry into the HOMO, and this is responsible for the differing effects of substitution.
- Hutchings, Michael G.,Meyrick, Barry H.,Nelson, Anthony J.
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p. 5081 - 5088
(2007/10/02)
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