Rhodium/bisphosphine-thiourea-catalyzed enantioselective hydrogenation of α,β-unsaturated: N -acylpyrazoles
We successfully extended our Rh/bisphosphine-thiourea (ZhaoPhos) catalytic system to asymmetric hydrogenation of α,β-unsaturated N-acylpyrazoles affording products with high yields and excellent enantioselectivities (up to 97% yield, 99% ee). The pyrazole
N-heterocyclic carbene-catalyzed cyclization of unsaturated acyl chlorides and ketones
A straightforward synthesis of optically active trifluoromethyl dihydropyranones and spirocyclic oxindole-dihydropyranones has been realized by the chiral N-heterocyclic carbenes-catalyzed cyclization of α,β- unsaturated β-methylacyl chlorides with activated trifluoromethyl ketones or isatin derivatives. Copyright
Shen, Li-Tao,Shao, Pan-Lin,Ye, Song
p. 1943 - 1948
(2011/10/13)
More Articles about upstream products of 1332645-49-4