- Phenylthioheterocyclic derivatives
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Compounds of the formula STR1 wherein n is a integer of 0 to 2; R1 ' and R2 ' are, independently, hydrogen, halogen, trifluoromethyl, lower alkoxy or lower alkyl; and X is pyrimidinyl, thiazolyl or STR2 wherein R is hydrogen, lower alkyl, aryl or ar-lower alkyl; provided that at least one or R1 ' and R2 ' is other than hydrogen, and their pharmaceutically acceptable acid addition salts, and an anti-inflammatory method utilizing a compound of the formula STR3 wherein n is an integer of 0 to 2; R1 and R2 are, independently, hydrogen, halogen, trifluoromethyl, nitro, amino, lower alkylamino, di-lower-alkylamino, lower alkoxy or lower alkyl; and X is pyrimidinyl, thiazolyl or STR4 wherein R is hydrogen, lower alkyl, aryl or ar-lower alkyl; and their pharmaceutically acceptable acid addition salts, are described.
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