- Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus
-
Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
- Bahnous, Mebarek,Bouraiou, Abdelmalek,Chelghoum, Meryem,Bouacida, Sofiane,Roisnel, Thierry,Smati, Farida,Bentchouala, Chafia,Gros, Philippe C.,Belfaitah, Ali
-
p. 1274 - 1278
(2013/03/14)
-
- A Pd-catalyzed double coupling reaction to 4,5-disubstituted imidazole alkynes
-
A palladium-catalyzed double coupling reaction of 4,5-diiodoimidazoles 2, which were prepared by diiodination of imidazole, and terminal alkynes provided the corresponding imidazole diynes 3.
- Kim,Kang,Ryu,Keum,Seo
-
p. 507 - 512
(2007/10/03)
-
- Electron Spin Resonance Studies of Electron Capture Processes. Part 7. ?* (3-Electron Covalent Bond) Radical Anions of Halogenoimidazoles
-
Exposure of dilute solutions of 4-bromo- and 4-iodo-2-methylimidazole, 5-bromo- and 5-iodo-1,2-dimethylimidazole, and 4,5-dibromo- and 4,5-diiodo-1,2-dimethylimidazole in methanol (CD3OD) or methyltetrahydrofuran (MeTHF) to 60Co γ-rays at 77 K resulted in electron addition to yield not the expected ?* radical anions but ?* radical anions.In these radical anions the SOMO is primarly the C-Hal ?* molecular orbital with little delocalisation into the imidazole ring, i.e. a 3-electron ? bond.On slowly increasing the temperature of the MeTHF solutions of the bromoimidazoles the hyperfine features for the ?* radical anions were lost but with no clear concomitant growth of features assignable to 4- or 5-imidazolyl radicals.However, for the iodoimidazoles (2), (4), and (6) in CD3OD a new species was observed on annealing.The same species was observed for all three iodo compounds and is assigned to iodine atoms weakly bonded to CD3OD molecules O(D)CD3>.The results are discussed in the light of the ?* and/or ?* species obtained from electron capture by other aromatic halides and other substituted imidazoles.
- Symons, Martyn C. R.,Bowman, W. Russell
-
p. 975 - 979
(2007/10/02)
-