COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS
A method of treating an ocular disorder in a subject associated with increased all-trans-retinal in an ocular tissue includes administering to the subject a therapeutically effective amount of a primary amine compound of formula (I); and pharmaceutically acceptable salts thereof.
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Paragraph 00259
(2016/06/14)
Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids
Spiral binding: A highly enantioselective hydrogenation of unsaturated heterocyclic acids has been developed by using chiral iridium/spirophosphino oxazoline catalysts (see scheme; BArF-=tetrakis[3,5- bis(trifluoromethyl)phenyl]borate, Boc=tert-butoxycarbonyl). This reaction provided an efficient method for the preparation of optically active heterocyclic acids with excellent enantioselectivities. Copyright
The enantioselective hydrogenation of 5,6-dihydro-2H-pyran-3-carboxylic acid over a cinchona alkaloid-modified palladium catalyst: Asymmetric synthesis of a cockroach attractant
A novel application of a cinchona-modified supported Pd catalyst is presented. The key step in the asymmetric synthesis of the cockroach attractant methyl (+)-tetrahydro-2H-pyran-3-carboxylate was the enantioselective hydrogenation of 5,6-dihydro-2H-pyran
Szori, Kornel,Szollosi, Gyoergy,Bartok, Mihaly
scheme or table
p. 1354 - 1358
(2009/02/04)
PURINE DERIVATIVES AS IMMUNOMODULATORS
The present invention includes novel compounds useful in the treatment of various disorders in particular infectious diseases, cancer, and allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, and as vaccine adjuvants
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Page/Page column 66-67
(2008/12/08)
Derivatives of 5,6-Dihydro-2H-pyran-3-carboxylic acid
Some derivatives of 5,6-dihydro-2H-pyran-3-carboxaldehyde (7) and of its oxidation product 5,6-dihydro-2H-pyran-3-carboxylic acid (8) have been prepared.The aldehyde derivatives as well as the amides and esters of 8 have been tested in an insecticidal/fun
Spreitzer, Helmut,Mueller, Petra,Buchbauer, Gerhard
p. 963 - 970
(2007/10/02)
Preparation of 3-formyl-5,6-dihydro-2H-pyran
3-Formyl-5,6-dihydro-2H-pyran is prepared by conversion of acrolein in the presence of water, acids and halohydrocarbons of 1 to 6 carbon atoms and 1 to 6 halogen atoms as solvents at from 60° to 150° C. The 3-formyl-5,6-dihydro-2H-pyran obtained by the n
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(2008/06/13)
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