- Synthesis of 1,2,3,4-tetrahydro-4-oxothieno[3,2-d]pyrimidine and perhydropyrimidine derivates from alkyl dicyanoacetates
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Nucleophilic addition of methyl 3-aminothiophene-2-carboxylate (2) as well as of β-alanine ethyl ester (11) to one CN group of the salts 1 of alkyl dicyanoacetates, followed by cyclization, yielded 1,2,3,4-tetrahydro-4-oxo- thieno[3,2-d]pyridimine derivat
- Neidlein, Richard,Sui, Zhihua
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p. 579 - 584
(2007/10/02)
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