A multi-component domino reaction for the direct access to polyfunctionalized indoles via intermolecular allylic esterification and indolation
A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15-30 min with water as the major byproduct, which makes work-up convenient.
Get Best Price for1353896-88-41-(4-chlorophenyl)-7-(1-(4-chlorophenyl)-2-(4-fluorophenyl)-4-hydroxy-1H-indol-3-yl)-2-(4-fluorophenyl)-6,7-dihydro-1H-indol-4(5H)-one