Studies on the total synthesis of lactonamycin: Synthesis of the fused pentacyclic B-F ring unit
This paper describes an approach towards the total synthesis of lactonamycin with the elaboration of a key pentacyclic unit. Key steps include the synthesis of benzyl bromide 8 in eight steps and 23 % overall yield starting from 4-methoxyphenol; a high-yi
Jacques, Sylvain A.,Michaelis, Simon,Gebhardt, Bjoern,Blum, Andreas,Lebrasseur, Nathalie,Larrosa, Igor,White, Andrew J. P.,Barrett, Anthony G. M.