Potassium Carbonate Promoted C-N Coupling Reaction between Benzamides and Aryl Iodides
A practical and efficient method for N-arylation of benz-amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).
Huang, Fei,Wu, San,Hu, Weiye,Zhang, Songlin
supporting information
p. 1090 - 1096
(2017/11/29)
Copper-catalysed intramolecular O-arylation of aryl chlorides and bromides: a straightforward approach to benzo[d]oxazoles in water
A general, efficient and more sustainable protocol for the copper-catalysed intramolecular O-arylation of o′-haloanilides leading to the benzo[d]oxazole core is reported. Remarkably, the optimised conditions allowed for the use of inexpensive and easily available aryl chlorides as arylating agents. Moreover, all reactions were carried out employing exclusively water as the solvent, rendering the methodology presented herein highly valuable from both environmental and economic points of view.
ELCTRON IMPACT MASS SPECTRA OF SOME 2',3'-, AND 4'-SUBSTITUTED THIOPHENE-2- AND 3-CARBOXANILIDES
The electron impact mass spectra (EI/MS) of 2- and 3-carboxanilides are dominated by the peak due to the corresponding thenoyl cations formed by cleavage of the C-N amide bond.This reaction is not affected by the polar effect of the substituents present in the phenyl ring.Most of the 2'-substituted derivatives undergo a cyclisation reaction with ejection of the substituent.In addition, for 2'-methyl and 2'-ethyl derivatives of both series of thiophene anilides a cryptic "ortho"-effect was suggested as responsible of the charge retention in the aniline moiety.
Barbieri, Cristina Lea,Ceraulo, Leopoldo,Maria, Paolo De,Fontana, Antonella,Spinelli, Domenico,Zuppiroli, Luca
p. 975 - 984
(2007/10/02)
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