Synthesis of 2′-substituted inosine analogs via unusual masking of the 6-hydroxyl group
(Chemical Equation Presented) 2′-Modified inosine analogs have been synthesized from 6-chloropurine riboside via 6-dimethylaminopurine or 6-benzyloxypurine intermediates. The dimethylaminopurine intermediate was obtained via an unusually facile dimethylam
Casu, Fabio,Harston, Rebecca K.,Chiacchio, Maria A.,Gumina, Giuseppe