- Controlled release system based on mesoporous silica nanoparticles and preparation method thereof
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The invention relates to a meso-porous silicon oxide nanoparticle-based controlled release system and a preparation method thereof, and concretely relates to a meso-porous silicon oxide-based nanoparticle for controlled release, a controlled release system containing the nanoparticle, and a preparation method and a kit of the nanoparticle. The nanoparticle contains a phenyl borate functionalized meso-porous silicon oxide nanoparticle and a surface functionalized nanoparticle hole plugging agent which can be combined with phenyl borate. When no substrate exists, a nanometer silicon oxide system in the invention can realize zero early release; and after the substrate is added, a meso-porous tunnel plugged by the nanoparticle is opened in order to realize controlled release of a content. The method has the advantages of simple material synthesis, adjustable composition, and realization of responses to different substrates and different concentrations.
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Paragraph 0129-0131
(2020/08/30)
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