Novel branched isocyanides as useful building blocks in the Passerini-amine deprotection-acyl migration (PADAM) synthesis of potential HIV-1 protease inhibitors
Novel branched isocyanides have been prepared from l-serine and used as building blocks in the Passerini-amine deprotection-acyl migration (PADAM) sequence for the preparation of compounds with activity against HIV-1 protease.
Gravestock, David,Rousseau, Amanda L.,Lourens, Anna C.U.,Hoppe, Heinrich C.,Nkabinde, Lindiwe A.,Bode, Moira L.
p. 3225 - 3229
(2012/07/31)
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