- Palladium-mediated coupling reactions of an amino-substituted heterocycle. Direct synthesis of C-nucleosides related to adenosine
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C-Nucleosides of the pyrazolo [1,5-a]-1,3,5-triazine aglycon system have been prepared by palladium-mediated coupling of 8-iodopyrazolo[1,5-a]-1,3,5-triazines. 4-(N,N'-Diisobutyloxycarbonyl)amino-8-iodopyrazolo[1,5-a]-1,3, 5-triazi ne and the furanoid gly
- Zhang,Brakta,Daves Jr.
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- Kinase inhibitors
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The present application is directed to pyrazolopyrirnidine and furopyrimidine analogs of the formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.
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