- Black yet green: A?heterogenous carbon-based acid catalyst for the synthesis of biscyclic derivatives under eco-friendly conditions
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In this study, a simple, cost-efficient and green protocol has been described for the synthesis of biscoumarin and bisdimedone derivatives via one-pot Knoevenagel–Michael reaction of aromatic aldehydes with 4-hydroxycoumarin and dimedone, respectively. Th
- Teli, Pankaj,Sethiya, Ayushi,Agarwal, Shikha
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p. 731 - 750
(2021/12/09)
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- Preparation and study of the catalytic application in the synthesis of xanthenedione pharmaceuticals of a hybrid nano-system based on copper, zinc and iron nanoparticles
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A novel efficiently mixed transition metal oxides catalytic system with high catalytic activity and heterogeneity constructed of copper and zinc oxide nanoparticles is presented. For preparation of this hybrid catalytic system, carrageenan as a natural polymeric matrix has been chosen to add biocompatibility to the heterogeneous catalyst. Then, the carrageenan textures have been magnetized through the composition with iron oxide nanoparticles. Copper and zinc metallic sites are employed as the main catalytic sites for catalyzing the synthesis of xanthenedione pharmaceutical derivatives from aldehyde and dimedone. Due to the magnetic behavior of the catalyst, the purification process is carried out with high convenience. Herein, a plausible mechanism for the catalytic process is suggested and reusability of the presented catalyst is also investigated. In this report, it has been well-proven that high reaction yields are obtained for xanthenedione derivatives under mild conditions, through applying the presented hybrid catalytic system.
- Esmaeili, Mir Saeed,Varzi, Zahra,Taheri-Ledari, Reza,Maleki, Ali
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p. 973 - 996
(2020/11/06)
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- Enhanced catalytic activity of bio-fabricated ZnO NPs prepared by ultrasound-assisted route for the synthesis of tetraketone and benzylidenemalonitrile in hydrotropic aqueous medium
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Abstract: Mushroom-like mesoporous and hexagonal ZnO nanoparticles were synthesized from plant extract and chemical method respectively, by co-precipitation method in aqueous medium. Different morphological forms of ZnO NPs were characterized by XRD, TGA, FESEM, EDX, FTIR, UV–Vis and BET. Neem (Azadirachta indica) leaf extract and ultrasound irradiation have a crucial role in the formation of different morphologies of ZnO NPs. ZnO NPs synthesized from plant extract and hydrotrope show a synergistic effect that leads to efficient synthesis of benzylidenemalonitrile and tetraketone derivatives at room temperature in water. Simple preparation of the catalyst, excellent yields, reusability of catalyst with consistent activity and ease of product isolation are the most significant advantages of this green protocol. Graphic abstract: [Figure not available: see fulltext.]
- Attar, Suraj R.,Kamble, Santosh B.,Shinde, Bipin
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- A reusable magnetic nickel nanoparticle based catalyst for the aqueous synthesis of diverse heterocycles and their evaluation as potential anti-bacterial agent
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A library of biologically important heterocycles, viz. pyrazolyl pyrimidine-triones, bis(heterocyclyl)methanes were successfully synthesised by the condensation of barbituric acid, pyrazolone with an aldehyde and dimedone/4-hydoxy coumarin with various su
- Bhattacharjee, Deboshikha,Sheet, Sanjoy Kumar,Khatua, Snehadrinarayan,Biswas, Koel,Joshi, Santaram,Myrboh, Bekington
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supporting information
p. 5018 - 5028
(2018/09/11)
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- Evaluation of sodium acetate trihydrate-urea des as a benign reaction media for the Biginelli reaction. Unexpected synthesis of methylenebis(3-hydroxy-5,5-dimethylcyclohex-2-enones), hexahydroxanthene-1,8-diones and hexahydroacridine-1,8-diones
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In this work, the low melting mixture sodium acetate trihydrate-urea was synthesized and the eutectic composition was determined and characterized using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The physical properties
- Navarro, Camilo A.,Sierra, Cesar A.,Ochoa-Puentes, Cristian
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p. 65355 - 65365
(2016/07/26)
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- Simple and cost effective acid catalysts for efficient synthesis of 9-aryl-1,8-dioxooctahydroxanthene
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CaCl2 (20 mol %) dispersion in DMSO or aq HBr (10 mol %) is developed as an efficient and cost effective acid catalyst for the simple one-pot synthesis of 9-aryl-1,8-dioxooctahydroxanthene derivatives. Reaction of aromatic aldehyde (1 equiv) an
- Ilangovan,Muralidharan,Sakthivel,Malayappasamy,Karuppusamy,Kaushik
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supporting information
p. 491 - 494
(2013/02/23)
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- Nickel nanoparticles: A highly efficient catalyst for one pot synthesis of tetraketones and biscoumarins
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A novel and practically useful protocol has been designed wherein, polyvinyl pyrrolidone (PVP) stabilized nickel nanoparticles have been used as a catalyst for promoting the synthesis of 2,2'-aryl-methylene bis(3-hydroxy-5,5- dimethyl-2-cyclohexene-1-one)
- Khurana, Jitender M.,Vij, Kanika
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p. 907 - 912,6
(2020/09/09)
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- Synthesis of 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-carboxylates and amides
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In an extension of Hantzsch aryldihydropyridine synthesis, 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-carboxylates (4) and 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-N-substituted amides (9) have been synthesised by the condensation of 5,5-dimethylcyclohexane-1,3-dione (dimedone) with aromatic aldehydes and β-aminocrotonates and β-aminocrotonamides.Compound 4 is also obtained by the reaction of bis-dimedonyl derivative (5) with β-aminocrotonate.Reaction of arylalkylidene acetoacetate (7) with dimedone and aq. ammonia or ammonium acetate also affords 4.
- Sainani, J. B.,Shah, A. C.,Arya, V. P.
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p. 526 - 531
(2007/10/03)
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- Chemistry of dimedone--Structures of aldehyde-dimedone adducts
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Novel features in the structures and stability of products of the hoary reaction of aldehydes with dimedone are described.Dimedone and cinnamaldehyde afford the bisdimedonyl derivative 3 or the perhydrochroman 5, while 4-dimethylaminocinnamaldehyde afford
- Nagarajan, K,Shenoy, S J
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