Practical Preparation of Chiral 4-Substituted 2-Oxazolidinones
A versatile and practical route to both enantiomers of a wide variety of 4-substituted 2-oxazolidinones from the parent heterocycle is provided by regioselective substitutions via 4-methoxy derivative followed by chromatographic separation of the diastereomers derived from N-2-exo-methoxy-1-apocamphanecarbonylation.