- 4-Deoxy-4-fluoro-xyloside derivatives as inhibitors of glycosaminoglycan biosynthesis
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Various 4-deoxy-4-fluoro-xylosides were prepared using click chemistry for evaluating their potential utility as inhibitors of glycosaminoglycan biosynthesis. 2,3-Di-O-benzoyl-4-deoxy-4-fluoro-β-d-xylopyranosylazide, obtained from l-arabinopyranose by six
- Tsuzuki, Yasuhiro,Nguyen, Thao Kim Nu,Garud, Dinesh R.,Kuberan, Balagurunathan,Koketsu, Mamoru
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supporting information; experimental part
p. 7269 - 7273
(2011/01/12)
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- Stereoselective synthesis of thioxylooligosaccharides from S-glycosyl isothiourea precursors
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A stereoselective synthesis of thioxylo-di-, -tri-, -tetra- and -penta-saccharides from S-glycosyl isothiourea precursors is described. The synthesis was performed starting from 2,3,4-tri-O-acetyl-β-D-xylopyranosyl isothiouronium bromide using a triethylamine promoted reaction with 1,2,3-tri-O-benzoyl-4-O-trifluoromethanesulphonyl-β-L-arabinopyranose. The resulting 4-thioxylobiose was then converted into the corresponding isothiouronium bromide and used for the synthesis of 4,4′-dithioxylotriose. Higher homologues of the series and their α-methyl glycosides were also prepared.
- Ibatullin, Farid M,Shabalin, Konstantin A.,J?nis, Janne V.,Selivanov, Stanislav I.
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p. 4565 - 4567
(2007/10/03)
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- Potential Antiviral Agents. Stereospecific Synthesis of Purines and Pyrimidines Substituted with Chiral Acyclic Chains by Sugar-Ring Opening of &α-L-Arabinopyranosyl Nucleosides
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3',4'-Seco-nucleosides as well as their derivatives lacking C-3', all retain the carbon framework and chirality of the β-D-ribofuranosyl moiety of the nucleosides occurring in nucleic acids, have been synthesized and their antiviral properties examined.Mo
- Perigaud, Christian,Gosselin, Gilles,Imbach, Jean-Louis
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p. 1943 - 1952
(2007/10/02)
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