Synthesis of oxadiazoles, thiadiazoles and triazoles derived from benzo[b]thiophene
In this work 3-chloro-2-chlorocarbonylbenzo[b]thiophene (1) was prepared from cinnamic acid and then converted into the acid hydrazide 2. The azomethines 3a-e were prepared from the corresponding aryl aldehydes and the acid hydrazide 2. Treatment of compo
Synthesis of novel 1,3,4-oxadiazole derivatives as potential antimicrobial agents
Some new 3-acetyl-5-(3-chloro-1-benzo[b]thiophen-2-yl)-2-substituted phenyl-2,3-dihydro-1,3,4-oxadiazoles and 2-(3-chloro-1-benzo[b]thiophen-2-yl)-5- substituted phenyl-1,3,4-oxadiazoles have been synthesized and evaluated for antimicrobial activity. Init
Benzo[b]thiophenes, II: Novel benzo[b]thienylhydrazine and 1,3,4-oxadiazole derivatives as potential antidepressant agents
Three novel series of benzo[b]thiophene derivatives bearing various hydrazone, hydrazine and 1,3,4-oxadiazole moieties were synthesized as potential antidepressant agents. 22 Compounds were evaluated for their in vitro inhibitory effect on monoamine oxida
AboulWafa,El-Metwalli
p. 603 - 608
(2007/10/02)
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