A practical synthesis of indoles via a Pd-catalyzed C-N ring formation
A method for the synthesis of N-functionalized C2-/C3-substituted indoles via Pd-catalyzed C-N bond coupling of halo-aryl enamines is described. The general strategy utilizes a variety of amines and β-keto esters which are elaborated into halo-aryl enamin
Vaswani, Rishi G.,Albrecht, Brian K.,Audia, James E.,Cote, Alexandre,Dakin, Les A.,Duplessis, Martin,Gehling, Victor S.,Harmange, Jean-Christophe,Hewitt, Michael C.,Leblanc, Yves,Nasveschuk, Christopher G.,Taylor, Alexander M.
p. 4114 - 4117
(2014/10/15)
MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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Paragraph 00264; 00265
(2013/08/28)
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