- 1-Substituted-1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-alkyloximes as novel orally active and long-lasting muscarinic cholinergic agonists
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Our previous attempts to design muscarinic agonists related to arecoline with the prerequisites for clinical use were successful with the discovery of 1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-methyloxime hydrochloride, RU 35963, and structurally rela
- Toja, E,Bonetti, C,Butti, A,Hunt, P,Fortin, M,et al.
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p. 519 - 526
(2007/10/02)
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- Oxime of 1, 2, 5, 6-tetrahydropyridine compounds their use as medicaments and the compositions containing them
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Compounds useful in the treatment of patients suffering from senile dementia, Alzheimer's disease or memory defects, of the formula STR1 in which R represents hydrogen or a linear, branched or cyclic alkyl, alkenyl, or alkynyl, containing up to 8 carbon a
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