Structure-activity requirements for flavone cytotoxicity and binding to tubulin
A series of 79 flavones related to centaureidin (3,6,4'-trimethoxy- 5,7,3'-trihydroxyflavone, 1) was screened for cytotoxicity in the NCI in vitro 60-cell line human tumor screen. The resulting cytotoxicity profiles of these flavones were compared for deg
Beutler, John A.,Hamel, Ernest,Vlietinck, Arnold J.,Haemers, Achiel,Rajan, Padinchare,Roitman, James N.,Cardellina II, John H.,Boyd, Michael R.
p. 2333 - 2338
(2007/10/03)
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