Novel compound capable of activating Nrf2, and pharmaceutical compositions comprising the same
The present invention provides a novel compound which can activate Nrf2 that is a transcription factor for expression of the quinone reductase gene. Therefore the compound is effective for inhibiting apoptosis and preventing and treating brain nerve disea
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(2016/10/08)
Synthesis and Nrf2 activating ability of thiourea and vinyl sulfoxide derivatives
Thiourea and vinyl sulfoxide derivatives were designed based on the structures of sulforaphane and gallic acid, prepared and tested for HO-1 inducing activity as a measure of Nrf2 activation, and inhibitory effect on NO production as a measure of anti-inf
Shim, Young Sun,Hwang, Hyun Sook,Nam, Ghilsoo,Choi, Kyung Il
supporting information
p. 2317 - 2320
(2013/09/24)
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