- New process for the synthesis of aminaphtone
-
The present invention concerns a new process for the synthesis of aminaphtone, which makes use of non-toxic solvents and reagents, under mild reaction and temperature conditions.
- -
-
Paragraph 0059; 0060
(2014/11/13)
-
- PROCESS FOR THE SYNTHESIS OF AMINAPHTONE
-
The present invention concerns a new process for the synthesis of aminaphtone, which makes use of non-toxic solvents and reagents, under mild reaction and temperature conditions. The aminaphtone obtained with the method of the present invention also has a purity of at least 98% in weight. The method comprises the following steps: a) epoxidating menadione 1 to provide epoxide 2, b) acidifying epoxide 2 to provide hydroxynaphthoquinone 3, c) esterifying between hydroxynaphthoquinone 3 and 4-aminobenzoyl chloride to obtain compound 4, and d) reducing compound 4 in the presence of a reducing agent in water to obtain aminaphtone.
- -
-
Paragraph 0075; 0076
(2014/11/11)
-
- Process for the preparation of aminaphtone
-
Herein described is a new process for the preparation of aminaphtone with high purity. Said process uses solvents with low toxicity, mild reaction conditions - such as temperature and pressure - within a short time.
- -
-
Page/Page column 5
(2011/12/12)
-