Synthesis and biological properties of 2-pyrrolidinoethoxy derivatives of 3,5-diarylpyrazoles and 2-pyrazolines
Cyclization of 2'-or 4'-hydroxy-4-methoxychalkone (1,2) with hydrazine hydrate in refluxing formic or acetic acid gives 1-acyl-5-aryl-3-(2-or 4-hydroxyphenyl)-2-pyrazolines (3-6).Alkylation of 1-6 and 4-hydroxy-3,5-diphenylpyrazole (17) with N-(2-chloroet