A potent new class of κ-receptor agonist: 4-Substituted 1-(arylacetyl)- 2-[(dialkylamino)methyl]piperazines
The synthesis of 4-substituted 1-(arylacetyl)-2- [(alkylamino)methyl]piperazines (10-22, 26, 27, and 30-33) and their activities as κ-opioid receptor agonists are described. This includes a range of 4-acyl and 4-carboalkoxy derivatives with the latter ser
Naylor,Judd,Lloyd,Scopes,Hayes,Birch
p. 2075 - 2083
(2007/10/02)
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