A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of γ-turn mimetics into a model substrate
C7 mimetics, designed to lock three amino acid residues of a peptide chain into a γ-turn conformation, were introduced sequentially between the P3 to P2' positions of a model HIV-1 protease substrate I (resulting in compou
Newlander,Callahan,Moore,Tomaszek Jr.,Huffman
p. 2321 - 2331
(2007/10/02)
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