An Approach to Features Responsible for the Obtention of High e.e. with a Highly Enantioselective NADH Model
A study of the reactivity of several NADH models with free, restricted or suppressed rotating ability of the amide carbonyl group suggests that the main factor responsible for the high e.e. obtained (94percent) with a cyclized reagent is an entropy featur
Combret, Yves,Duflos, Jack,Dupas, Georges,Bourguignon, Jean,Queguiner, Guy