- Preparative synthesis of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione (2-trifluoroacetyl Meldrum's acid) and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one and their synthetic usefulness as (trifluoroacetyl)ketene precursors
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A simple and reliable method for the preparation of 2,2-dimethyl-5-(trifluoroacetyl)-1,3-dioxane-4,6-dione and 2,2-dimethyl-6-(trifluoromethyl)-4H-1,3-dioxin-4-one on a multigram scale was developed. These (trifluoroacetyl)ketene precursors were used in the hetero-Diels-Alder reaction with dialkylcyanamides and 1-ethoxyprop-1-yne, as well as in some reactions with nucleophiles.
- Sevenard, Dmitri V.,Didenko, Andrey V.,Lorenz, Denis,Vorobiev, Michael,Stelten, Johannes,Dülcks, Thomas,Sosnovskikh, Vyacheslav Ya.
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p. 1495 - 1502
(2017/02/18)
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- Synthesis of novel 2-perfluoroacylcyclohexane-1,3-diones
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A one-pot synthesis of 2-perfluoroalkanoylcyclohexane-1,3-diones via C-acylation of cyclohexane-1,3-diones with N-perfluoroacylimidazole as an acylating agent is reported. A reaction was examined with isolated N-trifluoroacetylimidazole and with N-perfluoroacylimidazoles generated in situ from perfluorocarboxylic acid anhydrides or perfluorocarboxylic acids.
- Khlebnicova,Isakova,Baranovsky,Borisov,Lakhvich
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p. 1564 - 1569
(2008/09/18)
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- EFFICIENT OXYGENATION OF THIOPHOSPHORYL AND SELENOPHOSPHORYL GROUPS USING TRIFLUOROACETIC ANHYDRIDE
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Trifluoroacetic anhydride reacts with organophosphorus compounds containing thiophosphoryl and selenophosphoryl groups converting them in high yield to the corresponding oxygenated systems.
- Helinski, Jan,Skrzypczynski, Zbigniew,Wasiak, Jacek,Michalski, Jan
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p. 4081 - 4084
(2007/10/02)
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