6-methyl-2, 4-pyrimidyl diesters. A highly efficient acylating agent for the synthesis of unsymmetrical ketones
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Lee, Jae In
experimental part
p. 749 - 752
(2010/08/07)
Synthesis of 2,4-dibenzoyloxy-6-methylpyrimidine and its acylotropic transformations
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Podzigun, G. I.,Petrova, V. V.,Reznik, V. S.,Schagidullin, R. R.,Avvakumova, L. V.
p. 384 - 385
(2007/10/03)
Research on antiviral agents. 4. Studies on the chemistry of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2,4-di-O-acyloxypyrimidine derivatives as new acylation reagents and inhibitors of uracil DNA glycosylases.
The synthesis of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2,4-di-O-acyloxypyrimidine derivatives 2 and 5 along with their properties as acylating agents of amines, alcohols, thiols and α-amino acids have been reported. Interestingly some of the title products revealed an inhibitory activity against the human and herpetic DNA glycosylases.