Palladium-catalyzed c-2 selective olefination of thiazoles
A highly efficient protocol for C2 selective alkenylation of electron-deficient thiazoles is developed. High C2 position selectivity for alkenylation products is achieved at a neutral environment, and a possible pathway of oxidative alkenylation is discussed. This methodology provides a simple way to construct a 2-alkenyl-thiazole moiety.
Liu, Wei,Yu, Xin,Kuang, Chunxiang
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p. 1798 - 1801
(2014/04/17)
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