1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)
We have identified the N1-benzyl-N2-methylethane-1,2-diamine unit as a substitute for the (S)-alanine benzylamide moiety for the design of co-activator associated arginine methyltransferase 1 (CARM1) inhibitors. The potency of these
Studies Directed Towards the Total Synthesis of Vancomycin: Formation of Biphenyl Ether by Macrocyclisation
A simple methodology for the construction of D-O-E diphenyl ether 16-membered ring system present in Vancomycin by intramolecular displacement of fluorine by phenoxide reaction is described.
Rao, A V Rama,Reddy, K Laxma,Rao, A Srinivasa
p. 8465 - 8468
(2007/10/02)
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