This work describes the use of a 2,5,5-trisubstituted imidazoline as an amide bond replacement.The replacement is incorporated into dipeptide derivatives of Phe, Trp, Lys and Nle and also into the CCK-4 analogue Trp-Nle-Asp-Phe-NH2 and the pentagastrin an
Gilbert, Ian H.,Rees, David C.,Crockett, Alan K.,Jones, Raymond C. F.
p. 6315 - 6336
(2007/10/02)
Synthesis of A Homochiral α,α-Disubstituted α,β-Diamino-acid
The synthesis of a homochiral α,α-diamino-acid is described from norleucine using stereospecific alkylation of a homochiral oxazolidinone enolate; an optically active pseudotetrapeptide analogue of CCK-4 is prepared to show an application of such diamino-
Jones, Raymond C. F.,Crockett, Alan K.,Rees, David C.,Gilbert, Ian H.
p. 1661 - 1664
(2007/10/02)
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