Synthesis of 2-[(arylmethylene)amino]cyclopropanecarbonitriles via a two-step ring transformation of 2-(cyanomethyl)aziridines
Reaction of 2-(cyanomethyl)aziridines with N-bromosuccinimide in dichloromethane results in the formation of 3-[(arylmethylene) amino]-4-bromobutanenitriles in high yield. The latter α-amino-γ- bromobutanenitriles were converted into separable trans- and