Reaction of Trimethylsilylamines with N-Cbz-L-Serine-β-Lactone: A Convenient Route to Optically Pure β-Amino-L-alanine Derivatives
Trimethylsilylamines, Me3Si-NR2, react with N-Cbz-L-serine-β-lactone in acetonitrile primarily by alkyl oxygen cleavage of the lactone ring to give optically pure N-Cbz-β-amino-L-alanine derivatives in good yields.Use of halogenated sovents such as chloro
Ratemi, Elaref S.,Vederas, John C.
p. 7605 - 7608
(2007/10/02)
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