Enantioselective syntheses and resolution of the key White intermediate for the synthesis of trisporic acids
Two asymmetric syntheses of the alkylated cyclohexenone carboxylic acid moiety, the key White intermediate (4a), of trisporic acids A, B and C are described. The syntheses feature a Michael addition in tandem with an aldol condensation as the central step
Bacigaluppo, Jose A.,Colombo, Maria I.,Preite, Marcelo D.,Zinczuk, Juan,Ruveda, Edmundo A.,Sieler, Joachim
Enantioselective Synthesis of the White Key Intermediate for the Synthesis of Trisporic Acids
The asymmetric construction of the alkylated cyclohexenone carboxylic acid moiety of trisporic acids A, B and C and the syntheses of related precursors are described.The syntheses feature a Michael addition in tandem with an aldol condensation as the cent
Bacigaluppo, Jose A.,Colombo, Maria I.,Cravero, Raquel M.,Gonzalez-Sierra, Manuel,Preite, Marcelo D.,et al.