The first efficient biocatalytic route for the synthesis of Kojic acid derivatives in aqueous media
The first efficient biocatalytic route for the synthesis of kojic acid derivatives was developed in presence of an enzyme. In this process, benzaldehydes, malononitrile and kojic acid were used as starting materials while lipase from Aspergillus niger was
Dalal, Kiran S.,Chaudhari, Mangal A.,Dalal, Dipak S.,Chaudhari, Bhushan L.
MCM-41-SO3H: an efficient, reusable, heterogeneous catalyst for the one-pot, three-component synthesis of pyrano[3,2-b]pyrans
MCM-41-SO3H, ordered mesoporous silica material MCM-41 with covalently anchored sulfonic acid groups, was used as a solid acid catalyst for the convenient, efficient, and ‘green’ synthesis of 2-amino-6-(hydroxymethyl)-8-oxo-4-aryl-4,8-dihydropy
Green synthesis of pyrano [3,2-b]pyran derivatives using nano Si–Mg–fluorapatite catalyst and the evaluation of their antibacterial and antioxidant properties
In this study, we synthesize 2-amino-4-alkyl/aryl-6-(hydroxymethyl)-8-oxopyrano[3,2-b] pyran-3-carbonitriles derivatives using a multicomponent reaction featuring aromatic or aliphatic aldehydes, kojic acid, and malononitrile catalyzed by nano fluoroapati
Microwave-assisted, water-mediated Michael addition for synthesis of kojic acid derivatives
A highly efficient method is described for the synthesis of substituted kojic acid derivatives in the presence of water under microwave irradiation. This transformation represents an efficient way to synthesize kojic acid derivatives from simple starting
Likhar, Pravin R.,Reddy, G. Narshimha,Reddy, M. Ramana
p. 5983 - 5989
(2016/06/01)
Supramolecular catalysis by β-cyclodextrin for the synthesis of kojic acid derivatives in water
An efficient and green method has been developed for the synthesis of kojic acid derivatives by employing 20 mol% β-cyclodextrin in aqueous media. The high functional group tolerance and shorter reaction times make this method suitable for the synthesis o
Kataev, Evgeny A.,Ramana Reddy, Mittapalli,Niranjan Reddy, Gangarpu,Reddy, Vemulapati Hanuman,Suresh Reddy, Cirandur,Subba Reddy, Basi V.
p. 1693 - 1697
(2016/02/19)
SiO2-OSO3H nanoparticles: An efficient, versatile and new reagent for the one-pot synthesis of 2-amino-8-oxo-4,8-dihydropyrano[3,2-b] pyran-3-carbonitrile derivatives in water, a green protocol
In a one-pot three-component reaction, an aromatic or aliphatic aldehyde, malononitrile and 5-hydroxy-2-hydroxymethyl-4H-pyran-4-one were condensed for the synthesis of 2-amino-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile derivatives in the presence of nano-silica sulfuric acid (SiO 2-OSO3H nanoparticles) in improved yields. The catalyst is recoverable by simple filtration and can be used in the subsequent reactions.