New Synthesis of Isoxazolidines from the Selenium-Induced Cyclization of O-Allyl Hydroxylamines
The reaction of O-allyl hydroxylamines with phenylselenenyl sulfate, generated from the oxidation of diphenyl diselenide with ammonium persulfate, easily affords N-alkyl isoxazolidines as the result of a cyclization reaction through the formation of a car
Selenium-induced cyclization of O-allyl oximes as a synthetic route to N-alkyl isoxazolidines
Phenylselenyl bromide easily reacts with O-allyl oximes to afford cyclic iminium bromides which can be reduced in situ with sodium borohydride to produce substitued N-alkyl isoxazolidines in good yield.