Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies
Microtubule (MT) stabilizing drugs hold promise as potential treatments for Alzheimer's disease (AD) and related tauopathies. However, thus far epothilone D has been the only brain-penetrant MT-stabilizer to be evaluated in tau transgenic mice and in AD p
Lou, Kevin,Yao, Yuemang,Hoye, Adam T.,James, Michael J.,Cornec, Anne-Sophie,Hyde, Edward,Gay, Bryant,Lee, Virginia M.-Y.,Trojanowski, John Q.,Smith, Amos B.,Brunden, Kurt R.,Ballatore, Carlo
p. 6116 - 6127
(2014/08/18)
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