- Azelanitrile preparation method
-
The invention relates to an azelanitrile preparation method, which comprises: (1) dissolving glutaraldehyde in a solvent, adding a condensation catalyst and an optional cocatalyst, adding cyanoaceticacid in batches to maintain the temperature of the reaction solution of not more than 40 DEG C, and carrying out a condensation reaction, wherein a molar ratio of the glutaraldehyde to the cyanoaceticacid is 1:2; and (2) further adding a palladium carbon catalyst (Pd/C) to the condensation reaction liquid obtained in the step (1), introducing hydrogen gas, maintaining the pressure, heating, and carrying out a decarboxylation and hydrogenation reaction to obtain azelanitrile, wherein the hydrogen pressure is 3.0-4.0 MPa. According to the present invention, the method can perform the reaction by using the one-step method so as to eliminate the separation and purification process of the intermediate product, such that the reaction process is simple, and the cost is low.
- -
-
-
- METHOD FOR THE SYNTHESIS OF HIGH PURITY PRIMARY DIAMINES AND/OR TRIAMINES
-
The present invention relates to a process for the preparation of primary di- and/or triamines of high purity from nitriles which can themselves originate from dimer and/or trimer acids. This process comprises a stage of ammoniation of the acid functional groups and a stage of hydrogenation of the nitrile functional groups to give primary amine functional groups and does not require additional purification stage(s).
- -
-
Page/Page column 5
(2011/08/08)
-
- Mg/MeOH mediated intramolecular reductive cyclization of activated dienes
-
Facile intramolecular cyclisation of activated tethered dienes mediated by magnesium in methanol at room temperature is described.
- Chavan, Subhash P.,Ethiraj, Krishna S.
-
p. 2281 - 2284
(2007/10/02)
-
