Synthesis of a 5-alkoxypyrido[4,3-d]pyrimidin-4(3H)-one derivative via a regioselective Meisenheimer N-oxide rearrangement
The synthetic strategy towards a 5-alkoxypyrido[4,3-d]pyrimidin-4(3H)-one is described utilizing a selective N-oxidation and subsequent regioselective Meisenheimer N-oxide rearrangement as key steps.
Williams, Emma J.,Kenny, Peter W.,Kettle, Jason G.,Mwashimba, Paul G.
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
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(2008/06/13)
3,7-Dihydro- and 1,7-dihydro-4H-pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-4-ones
New 3,7-dihydro and 1,7-dihydro-4H-pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-4-ones which have the general formula STR1 are useful as anti-inflammatory agents and central nervous system depressants.
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(2008/06/13)
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