Synthesis of New 1,8-Bridged Tricyclic Quinolones by a Novel Intramolecular Arylation of N-1 Tethered Malonamides
An efficient process for the preparation of 2,7-dioxopyridocinnolines by a novel intramolecular arylation reaction of N-1 tethered quinolone malonamides is described.The application of this methodology to the synthesis of some novel tricyclic q