Reductive Cleavage of N-Substituted 2-Aryl-1,3-oxazolidines: Generation of α-Amino-Substituted Carbanions
The behavior of several N-substituted 2-aryl-1,3-oxazolidines has been investigated under conditions of electron transfer from alkali metals in aprotic solvents.The reduction led to the regioselective cleavage of the benzylic carbon-oxygen bond, with formation of the corresponding N-substituted benzylamino alcohols in good yields.Investigation of the mechanism of this reductive cleavage, with the aid of labeling experiments, showed the intermediate formation of α-tertiary amino-substituted carbanions.
Azzena, Ugo,Melloni, Giovanni,Nigra, Cristina
p. 6707 - 6711
(2007/10/02)
Thermal Rearrangement of some Oxazolidine N-Oxides. 2-Alkyl-6-aryl-3,4-dihydro-2H-1,5,2-dioxazines
3-Alkyl-2-aryloxazolidines are oxidized with 3-chloroperoxybenzoic acid to produce the corresponding oxazolidine N-oxides.These N-oxides undergo thermal rearrangement to give 2-alkyl-6-aryl-3,4-dihydro-2H-1,5,2-dioxazines in 55-85 percent yield.
Saba, Shahrokh,Domkowski, Patrick W.,Firooznia, Fariborz
p. 921 - 923
(2007/10/02)
More Articles about upstream products of 1741-81-7