Simple one-pot process for the bioresolution of tertiary amino ester protic ionic liquids using subtilisin
An efficient hydrolase-catalyzed bioresolution of tertiary amino ester protic ionic liquids has been demonstrated. Protic ionic liquids have been prepared in one step from the corresponding tertiary amino alcohols by treatment with butyric anhydride. Afte
Brossat, Maude,Moody, Thomas S.,Taylor, Stephen J.C.,Wiffen, Jonathan W.
experimental part
p. 2112 - 2116
(2010/02/28)
Interactions of chiral quinuclidin-3-yl benzoates with butyrylcholinesterase: Kinetic study and docking simulations
Both enantiomers of quinuclidin-3-yl benzoate (RQBz and SQBz) were synthesized in order to examine the stereoselectivity of the hydrolysis of these esters catalyzed by horse serum butyrylcholinesterase (BChE). The hydrolysis of benzoylcholine (BzCh) was a