cas 175135-68-9, 2-[(5-AMINO-1,3,4-THIADIAZOL-2-YL)THIO]-5-NITROBENZONITRILE | Articles data ｜lookchem

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175135-68-9

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Design and synthesis of new heterocyclic Bcr-Abl inhibitors
Herein, a series of heterocyclic Bcr-Abl kinase inhibitors with different structural scaffolds were designed and synthesized. HTScan Abll kinase assay kit was used for the inhibitory test. Some modest inhibitors were obtained.
Chen, Yong-Fei,Ni, Nanting,Li, Minyong,Xu, Peng-Fei,Wang, Binghe
experimental part
p. 123 - 135
(2011/06/26)

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Chemical Properties

Melting Point: 245-246oC
Boiling Point: 545.4oC at 760 mmHg
Flash Point:283.6oC
Density: 1.69g/cm3
Vapor Pressure: 5.96E-12mmHg at 25°C
PSA: 174.95000
LogP: 3.15578

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