SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION
The invention relates to substituted cyclohexyl-1,4-diamine derivatives, to a method for their production, to medicaments containing said compounds and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicaments.
2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide and close analogues inhibit glucose stimulated insulin release through activation of Kir6.2/SUR1 KATP channels of beta cells.
Nielsen, Flemming E.,Jacobsen, Palle,Worsaae, Anne,Arkhammar, Per O.G.,Wahl, Philip,Bondo Hansen, John
p. 5727 - 5730
(2007/10/03)
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