- AMINOETHANOL DERIVATIVES
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The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formula wherein Ar1 is an aromatic ring group optionally having substituents, Ar2 is an aromatic ring group having substituents, OR'' is an optionally protected hydroxyl group, R is an acyl group, R' is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.
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Page/Page column 125
(2010/11/30)
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- Trifluoromethylated Furans via Iodocyclisation of γ-Unsaturated Ethyl Trifluoroacetoacetates
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Under iodoetherification conditions, γ-unsaturated ethyl trifluoroacetoacetates 1a-c exhibit a specific reactivity.Conditions were found for the synthesis of cyclic iodo hemiketals 2a-c and for their subsequent conversion into either α-trifluoromethylated
- Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Dogbeavou, Romain,Ourevitch, Michele
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p. 2787 - 2792
(2007/10/02)
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