Domino Suzuki coupling and condensation reaction: An efficient strategy towards synthesis of phenanthridines
A short and convenient hetero-annulation protocol has been developed for the synthesis of substituted phenanthridines via domino Suzuki coupling and condensation between N-(2-iodo-aryl)-formamide derivatives and 2-formylphenylboronic acid in the presence of Pd(OAc)2, Cs2CO3 and PPh3 as catalytic system in dry DMF at 85-90 °C for 6-7 h. The intermediate after Suzuki coupling and deprotection of nitrogen under the same catalytic system, furnishes the corresponding phenanthridines in good yields after immediate condensation and dehydration.
Ghosh, Munmun,Ahmed, Atiur,Singha, Raju,Ray, Jayanta K.
supporting information
p. 353 - 355
(2015/03/05)
Luminescent sensors for pH, pO2, halide and hydroxide ions using phenanthridine as a photosensitiser in macrocyclic europium and terbium complexes
The metal-based luminescence of the Eu and Tb complexes of the octadentate ligands L1 and L2a/2b is a function of pH in aqueous solution:in [EuL1], the red-emission is switched on following N-protonation of the sensitising
Parker, David,Senenayake, P. Kanthi,Williams, G. A. Gareth
p. 2129 - 2140
(2007/10/03)
Intramolecular Addition of Aryl Radicals to Carbon-Nitrogen Double Bonds
Cyclisation of radicals 6a,b is highly regioselective towards a 5-exo process; 6-endo ring closure is a minor route and their ratio depends on the substituents.No ring expansion of the five-membered radical intermediates 7a,b was observed.Radicals 27a,b give rise to 5-exo cyclisation regiospecifically.A competitive 1,5-hydrogen shift leading to imidoyl radicals was noticed.An analogous behaviour is also exhibited by vinyl radicals when allowed to add to carbon-nitrogen double bonds.
Gioanola, Milena,Leardini, Rino,Nanni, Daniele,Pareschi, Patrizia,Zanardi, Giuseppe
p. 2039 - 2054
(2007/10/02)
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