Synthesis and acaricidal activity of 4-pyrimidinyloxy- and 4- pyrimidinylaminoethylphenyl dioxolanes and oxime ethers
Novel types of mitochondrial respiration inhibitors at complex I, with emphasis on acaricidal activity, have been designed and prepared. The synthetic approach to these 4-pyrimidinylphenyl ethyl ethers and amines with a specific ketal or oxime function in the phenyl side chain is outlined. Bioassays demonstrate their high potential against important spider mites, like Tetranychus urticae and Panonychus ulmi. Structure-activity relationship studies and several biological parameters are discussed. (C) 2000 Society of Chemical Industry.
Lamberth, Clemens,Hillesheim, Elke,Bassand, Denis,Schaub, Fritz
p. 94 - 100
(2007/10/03)
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