- Esters of quinoxaline-1,4-dioxides
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Disclosed herein are novel esters of quinoxaline-1,4-dioxide of the structure SPC1 In which X is selected from the group consisting of a single bond, lower n-alkylene and --(CH2)p --CH=CH--(CH2)q -- where p and q may have integral values from zero to four with the proviso that p+q is less than or equal to four; A is selected from the group consisting of hydrogen, hydroxyl, lower alkyl, lower alkoxy, fluorine, chlorine, bromine, iodine, cyano and trifluoromethyl; And R is selected from the group consisting of hydrogen, lower alkanoyl and α-hydroxy lower alkyl. When administered to animals, these compounds function as antibacterial agents, promote growth and improve feed efficiency. They are particularly useful in the prophylaxis and treatment of pasturellosis and salmonellosis and are notable for their extremely low toxicity in the test animal.
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