- Synthesis of the lipophilic antifolate piritrexim via a palladium(0)-catalyzed cross-coupling reaction
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(Chemical Equation Presented) A regiospecific and convergent route the lipophilic antifolate piritrexim (PTX) is described in which a key step is a Pd(0)-catalyzed cross-coupling reaction between 2-amino-3-cyano-4-methyl-5- bromopyridine and 2,5-dimethoxy
- Chan, David C. M.,Rosowsky, Andre
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p. 1364 - 1368
(2007/10/03)
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- 2,4-diamino-5,6-disubstituted- and 5,6,7-trisubstituted 5-deazapteridines as insecticides
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An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a 5-deazapteridine compound of the formula: STR1 wherein R1, R2, R3, R4, U, V, and W are as defined herein; agriculturally acceptable salts thereof; methods for using the same; and certain novel 5-deazapteridines per se.
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